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The Effect of Exposure to a High-Fat Diet on MicroRNA Expression in the Liver of Blunt Snout Bream (Megalobrama amblycephala)
文献类型:期刊论文
作者:Zhang, Dingdong[1]  Lu, Kangle[2]  Dong, Zaijie[3]  Jiang, Guangzhen[4]  Xu, Weina[5]  Liu, Wenbin[6]  
机构排名:[1]Nanjing Agr Univ, Coll Anim Sci & Technol, Key Lab Aquat Nutr & Feed Sci Jiangsu Prov, Nanjing, Jiangsu, Peoples R China.;Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Key Lab Freshwater Fisheries & Germplasm Resource, Wuxi, Peoples R China.,Nanjing Agr Univ, Wuxi Fisheries Coll, Wuxi, Peoples R China.;
[2]Nanjing Agr Univ, Coll Anim Sci & Technol, Key Lab Aquat Nutr & Feed Sci Jiangsu Prov, Nanjing, Jiangsu, Peoples R China.;
[3]Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Key Lab Freshwater Fisheries & Germplasm Resource, Wuxi, Peoples R China.,Nanjing Agr Univ, Wuxi Fisheries Coll, Wuxi, Peoples R China.;
[4]Nanjing Agr Univ, Coll Anim Sci & Technol, Key Lab Aquat Nutr & Feed Sci Jiangsu Prov, Nanjing, Jiangsu, Peoples R China.;
[5]Nanjing Agr Univ, Coll Anim Sci & Technol, Key Lab Aquat Nutr & Feed Sci Jiangsu Prov, Nanjing, Jiangsu, Peoples R China.;
[6]Nanjing Agr Univ, Coll Anim Sci & Technol, Key Lab Aquat Nutr & Feed Sci Jiangsu Prov, Nanjing, Jiangsu, Peoples R China.;
通讯作者:Dong, ZJ (reprint author), Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Key Lab Freshwater Fisheries & Germplasm Resource, Wuxi, Peoples R China.
年:2014
期刊名称:PLOS ONE影响因子和分区
卷:9
期:5
增刊:正刊
收录情况:SCI(E)(WOS:000336655700058)  
所属部门:淡水渔业研究中心;罗非鱼和鲤鱼遗传育种创新团队
语言:外文
ISSN:1932-6203
被引频次:23
人气指数:507
浏览次数:507
基金:National Natural Science Foundation of China [60901053, 31172418, 31202005]; Open Fund of Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Ministry of Agriculture, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences [KF201310]; "333" Projects of Jiangsu Province
摘要:
Blunt snout bream (Megalobrama amblycephala) are susceptible to hepatic steatosis when maintained in modern intensive culture systems. The aim of this study was to investigate the potential roles of microRNAs (miRNAs) in diet-induced hepatic steatosis in this species. MiRNAs, small non-coding RNAs that regulate gene expression at the posttranscriptional level, are involved in diverse biological processes, including lipid metabolism. Deep sequencing of hepatic small RNA libraries from blunt snout ...More
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