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Gut-Liver Immune Response and Gut Microbiota Profiling Reveal the Pathogenic Mechanisms of Vibrio harveyi in Pearl Gentian Grouper (Epinephelus lanceolatus male x E. fuscoguttatus female)
文献类型:期刊论文
作者:Deng, Yiqin[1]  Zhang, Yaqiu[2]  Chen, Haoxiang[3]  Xu, Liwen[4]  Wang, Qian[5]  Feng, Juan[6]  
机构排名:[1]Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Key Lab South China Sea Fishery Resources Exploit, Minist Agr & Rural Affairs, Guangzhou, Peoples R China.;Chinese Acad Fishery Sci, Trop Aquaculture Res & Dev Ctr, South China Sea Fisheries Res Inst, Haikou, Hainan, Peoples R China.;
[2]Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Key Lab South China Sea Fishery Resources Exploit, Minist Agr & Rural Affairs, Guangzhou, Peoples R China.;Shanghai Ocean Univ, Coll Fisheries & Life Sci, Shanghai, Peoples R China.;
[3]Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Key Lab South China Sea Fishery Resources Exploit, Minist Agr & Rural Affairs, Guangzhou, Peoples R China.;Shanghai Ocean Univ, Coll Fisheries & Life Sci, Shanghai, Peoples R China.;
[4]Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Key Lab South China Sea Fishery Resources Exploit, Minist Agr & Rural Affairs, Guangzhou, Peoples R China.;
[5]Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Key Lab South China Sea Fishery Resources Exploit, Minist Agr & Rural Affairs, Guangzhou, Peoples R China.;
[6]Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Key Lab South China Sea Fishery Resources Exploit, Minist Agr & Rural Affairs, Guangzhou, Peoples R China.;Chinese Acad Fishery Sci, Trop Aquaculture Res & Dev Ctr, South China Sea Fisheries Res Inst, Haikou, Hainan, Peoples R China.;
通讯作者:Feng, J (corresponding author), Chinese Acad Fishery Sci, South China Sea Fisheries Res Inst, Key Lab South China Sea Fishery Resources Exploit, Minist Agr & Rural Affairs, Guangzhou, Peoples R China.; Feng, J (corresponding author), Chinese Acad Fishery Sci, Trop Aquaculture Res & Dev Ctr, South China Sea Fisheries Res Inst, Haikou, Hainan, Peoples R China.
年:2020
期刊名称:FRONTIERS IN IMMUNOLOGY影响因子和分区
卷:11
增刊:正刊
收录情况:SCI(E)(WOS:000597278300001)  
所属部门:南海水产研究所;花鲈基因资源评价与遗传育种创新团队
语言:外文
ISSN:1664-3224
被引频次:1
人气指数:200
浏览次数:200
基金:National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [31902415]; Natural Science Fund of GuangdongNational Natural Science Foundation of Guangdong Province [2018A030310695, 2019A1515011833]; Hainan Provincial Natural Science Foundation of China [319QN336]; Central Public-interest Scientific Institution Basal Research Fund, South China Sea Fisheries Research Institute, CAFS [2019TS04]; Central Public-interest Scientific Institution Basal Research Fund, CAFS [2019ZD0707]
关键词:Vibrio harveyi; pearl gentian grouper; immune response; gut microbiota; interplay; pathogenesis
摘要:
Vibrio harveyi causes vibriosis in nearly 70% of grouper (Epinephelus sp.), seriously limiting grouper culture. As well as directly inhibiting pathogens, the gut microbiota plays critical roles in immune homeostasis and provides essential health benefits to its host. However, there is still little information about the variations in the immune response to V. harveyi infection and the gut microbiota of grouper. To understand the virulence mechanism of V. harveyi in the pearl gentian grouper, we i ...More
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